cell cycle checkpoint/DNA repair antagonist IC83

{
  "id": "MLC-T-ONC-012505",
  "term": "cell cycle checkpoint/DNA repair antagonist IC83",
  "field": "Oncology and biomedicine",
  "definition": "A proprietary agent with potential antineoplastic activity. IC83 appears to target cell cycle checkpoint/DNA repair enzymes, which are involved in the recognition and repair of damaged DNA and are overexpressed in many types of cancer cells. Inhibition of cell cycle checkpoint/DNA repair enzymes may enhance the cytotoxicity of DNA damaging agents and dissipate tumor cell resistance to chemotherapy and radiation therapy.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/cell-cycle-checkpoint-dna-repair-antagonist-ic83/"
}