Candida antigen extract patch VDMN-21
Term · Oncology and biomedicine · MLC-T-ONC-012222
An dissolvable microarray-based formulation containing an extract of Candida albicans (C. albicans) antigens, with immunomodulatory activity. Upon administration of the C. albicans antigen extract patch VDMN-21 adjacent to the cutaneous human papilloma virus (HPV)-infected wart(s), the C. albicans antigens, upon release from the microarray, stimulate the immune system to mount a cytotoxic T-lymphocyte (CTL)-mediated immune response against the C. albicans antigens and cause a delayed type hypersensitivity response against other local antigens, including antigens within the wart tissue. This leads to the production of Th1 cytokines, and the activation of natural killer (NK) cell- and CTL- mediated killing of HPV-infected cells. This causes clearing of both local and distant warts, and prevents HPV infection and wart formation that results from HPV infection.
| Identifier | MLC-T-ONC-012222 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | Candida antigen extract-containing microneedle patch VDMN-21; C. albicans antigen extract patch VDMN-21 |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-012222",
"term": "Candida antigen extract patch VDMN-21",
"field": "Oncology and biomedicine",
"definition": "An dissolvable microarray-based formulation containing an extract of Candida albicans (C. albicans) antigens, with immunomodulatory activity. Upon administration of the C. albicans antigen extract patch VDMN-21 adjacent to the cutaneous human papilloma virus (HPV)-infected wart(s), the C. albicans antigens, upon release from the microarray, stimulate the immune system to mount a cytotoxic T-lymphocyte (CTL)-mediated immune response against the C. albicans antigens and cause a delayed type hypersensitivity response against other local antigens, including antigens within the wart tissue. This leads to the production of Th1 cytokines, and the activation of natural killer (NK) cell- and CTL- mediated killing of HPV-infected cells. This causes clearing of both local and distant warts, and prevents HPV infection and wart formation that results from HPV infection.",
"synonyms": [
"Candida antigen extract-containing microneedle patch VDMN-21",
"C. albicans antigen extract patch VDMN-21"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/candida-antigen-extract-patch-vdmn-21/"
}
Record 4,087 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.