carnosine
Term · Oncology and biomedicine · MLC-T-ONC-012315
A dipeptide comprised of a beta-alanine and a 3-methyl-L-histidine, which is found in dietary red meat, with potential antioxidant, metal-chelating and anti-glycation activities. Carnosine scavenges both reactive oxygen species (ROS) and unsaturated aldehydes produced by cell membrane lipid peroxidation. Additionally, this dipeptide may reduce the rate of formation of advanced glycation end-products (AGE). Altogether, this may protect cells against oxidative damage. In addition, carnosine is able to chelate toxic metals.
| Identifier | MLC-T-ONC-012315 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | (2S)-2-[(3-amino-1-oxopropyl)Amino]-3-(3H-imidazol-4-Yl)propanoic acid; beta-alanyl-L-histidine; beta-alanylhistidine; L-histidine, beta-alanyl-; L-histidine, N-beta-alanyl- |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-012315",
"term": "carnosine",
"field": "Oncology and biomedicine",
"definition": "A dipeptide comprised of a beta-alanine and a 3-methyl-L-histidine, which is found in dietary red meat, with potential antioxidant, metal-chelating and anti-glycation activities. Carnosine scavenges both reactive oxygen species (ROS) and unsaturated aldehydes produced by cell membrane lipid peroxidation. Additionally, this dipeptide may reduce the rate of formation of advanced glycation end-products (AGE). Altogether, this may protect cells against oxidative damage. In addition, carnosine is able to chelate toxic metals.",
"synonyms": [
"(2S)-2-[(3-amino-1-oxopropyl)Amino]-3-(3H-imidazol-4-Yl)propanoic acid",
"beta-alanyl-L-histidine",
"beta-alanylhistidine",
"L-histidine, beta-alanyl-",
"L-histidine, N-beta-alanyl-"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/carnosine/"
}
Record 4,274 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.