CD56-enriched CD3-positive donor lymphocytes

{
  "id": "MLC-T-ONC-012415",
  "term": "CD56-enriched CD3-positive donor lymphocytes",
  "field": "Oncology and biomedicine",
  "definition": "A population of CD3-positive lymphocytes expressing the CD56 surface antigen, with potential immunomodulating activity. Upon infusion of the CD56-enriched CD3-positive donor lymphocytes, these cells may facilitate the reconstitution of CD4-positive T cells, regulatory T cells (Tregs) and natural killer (NK) cells, which may reduce the incidence of post-transplant graft-versus-host disease (GvHD) following haploidentical stem cell transplant (SCT). CD56 is a transmembrane glycoprotein also known as neural cell adhesion molecule 1 (NCAM-1).",
  "synonyms": [
    "CD56-enriched donor lymphocytes",
    "CD56-enriched donor cells",
    "CD56+/CD3+ donor cells"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/cd56-enriched-cd3-positive-donor-lymphocytes/"
}