allogeneic CD56-positive CD3-negative natural killer cells CYNK-001

{
  "id": "MLC-T-ONC-009858",
  "term": "allogeneic CD56-positive CD3-negative natural killer cells CYNK-001",
  "field": "Oncology and biomedicine",
  "definition": "A population of cryopreserved, off-the-shelf (OTS) allogeneic natural killer (NK) cells derived from human placental hematopoietic stem cells (HSCs) and expressing the CD56 surface antigen and exhibiting a lack of CD3, with potential immunomodulating, antineoplastic and antiviral activities. Upon infusion of allogeneic CD56-positive CD3-negative NK cells CYNK-001, these cells are able to recognize tumor cells as well as virally-infected cells, secrete perforins, granzymes and cytokines, and induce apoptosis in tumor and virally-infected cells.",
  "synonyms": [
    "allogeneic CD56+/CD3- natural killer cells CYNK-001",
    "allogeneic human placental hematopoietic stem cell-derived natural killer cells CYNK-001",
    "CD56+/CD3- NK cells CYNK-001",
    "natural killer cells CYNK-001",
    "human placental HSC-derived CD56+/CD3- NKs CYNK-001"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/allogeneic-cd56-positive-cd3-negative-natural-killer-cells-cynk-001/"
}