DHFR inhibitor

{
  "id": "MLC-T-ONC-002402",
  "term": "DHFR inhibitor",
  "field": "Oncology and biomedicine",
  "definition": "A substance that can build up in cancer cells and block them from using folate. Folate is a nutrient that rapidly dividing cells need to make DNA. Blocking folate use helps keep cancer cells from growing and may kill them. Some DHFR inhibitors are used to treat cancer. A DHFR inhibitor is a type of antifolate. Also called dihydrofolate reductase inhibitor.",
  "synonyms": [
    "dihydrofolate reductase inhibitor"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/dhfr-inhibitor/"
}