Degarelix acetate

{
  "id": "MLC-T-ONC-002340",
  "term": "Degarelix acetate",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A drug used to treat advanced prostate cancer. Degarelix acetate binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland. This causes the testicles to stop making testosterone. Degarelix acetate may stop the growth of cancer cells that need testosterone to grow. It is a type of GnRH antagonist. Also called Firmagon.",
    "The acetate form of a long-acting, synthetic peptide with gonadotrophin-releasing hormone (GnRH) antagonistic properties. Degarelix targets and blocks GnRH receptors located on the surfaces of gonadotroph cells in the anterior pituitary, thereby reducing secretion of luteinizing hormone (LH) by pituitary gonadotroph cells and so decreasing testosterone production by interstitial (Leydig) cells in the testes."
  ],
  "synonyms": [
    "Firmagon",
    "FE200486 acetate hydrate"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/degarelix-acetate/"
}