MLchartDataset catalogue

dihydro-5-azacytidine

Term · Oncology and biomedicine · MLC-T-ONC-013051

A synthetic nucleoside analogue of deoxycytidine. Dihydro-5-azacytidine inhibits DNA methyltransferase, thereby interfering with abnormal DNA methylation patterns that are associated with genetic instability in some tumor cells. Inhibition of this enzyme may restore expression of tumor-suppressor genes and result in antitumor activity.

Table 1. Record
IdentifierMLC-T-ONC-013051
FieldOncology and biomedicine
AbbreviationDHAC
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-013051",
  "term": "dihydro-5-azacytidine",
  "field": "Oncology and biomedicine",
  "definition": "A synthetic nucleoside analogue of deoxycytidine. Dihydro-5-azacytidine inhibits DNA methyltransferase, thereby interfering with abnormal DNA methylation patterns that are associated with genetic instability in some tumor cells. Inhibition of this enzyme may restore expression of tumor-suppressor genes and result in antitumor activity.",
  "abbreviation": "DHAC",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/dihydro-5-azacytidine/"
}

Record 6,004 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.