dihydro-5-azacytidine
Term · Oncology and biomedicine · MLC-T-ONC-013051
A synthetic nucleoside analogue of deoxycytidine. Dihydro-5-azacytidine inhibits DNA methyltransferase, thereby interfering with abnormal DNA methylation patterns that are associated with genetic instability in some tumor cells. Inhibition of this enzyme may restore expression of tumor-suppressor genes and result in antitumor activity.
| Identifier | MLC-T-ONC-013051 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | DHAC |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-013051",
"term": "dihydro-5-azacytidine",
"field": "Oncology and biomedicine",
"definition": "A synthetic nucleoside analogue of deoxycytidine. Dihydro-5-azacytidine inhibits DNA methyltransferase, thereby interfering with abnormal DNA methylation patterns that are associated with genetic instability in some tumor cells. Inhibition of this enzyme may restore expression of tumor-suppressor genes and result in antitumor activity.",
"abbreviation": "DHAC",
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/dihydro-5-azacytidine/"
}
Record 6,004 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.