deoxycytidine analogue TAS-109
Term · Oncology and biomedicine · MLC-T-ONC-012981
An analogue of the nucleoside deoxycytidine with potential antineoplastic activity. Nucleoside analogue TAS-109 is incorporated into DNA and directly inhibits the activity of DNA polymerase, which may result in inhibition of DNA replication and cell cycle arrest in the S and G2/M phases, DNA fragmentation, and tumor cell apoptosis.
| Identifier | MLC-T-ONC-012981 |
|---|---|
| Field | Oncology and biomedicine |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-012981",
"term": "deoxycytidine analogue TAS-109",
"field": "Oncology and biomedicine",
"definition": "An analogue of the nucleoside deoxycytidine with potential antineoplastic activity. Nucleoside analogue TAS-109 is incorporated into DNA and directly inhibits the activity of DNA polymerase, which may result in inhibition of DNA replication and cell cycle arrest in the S and G2/M phases, DNA fragmentation, and tumor cell apoptosis.",
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/deoxycytidine-analogue-tas-109/"
}
Record 5,835 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.