MLchartDataset catalogue

deoxycytidine analogue TAS-109

Term · Oncology and biomedicine · MLC-T-ONC-012981

An analogue of the nucleoside deoxycytidine with potential antineoplastic activity. Nucleoside analogue TAS-109 is incorporated into DNA and directly inhibits the activity of DNA polymerase, which may result in inhibition of DNA replication and cell cycle arrest in the S and G2/M phases, DNA fragmentation, and tumor cell apoptosis.

Table 1. Record
IdentifierMLC-T-ONC-012981
FieldOncology and biomedicine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-012981",
  "term": "deoxycytidine analogue TAS-109",
  "field": "Oncology and biomedicine",
  "definition": "An analogue of the nucleoside deoxycytidine with potential antineoplastic activity. Nucleoside analogue TAS-109 is incorporated into DNA and directly inhibits the activity of DNA polymerase, which may result in inhibition of DNA replication and cell cycle arrest in the S and G2/M phases, DNA fragmentation, and tumor cell apoptosis.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/deoxycytidine-analogue-tas-109/"
}

Record 5,835 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.