3-deazauridine

{
  "id": "MLC-T-ONC-009537",
  "term": "3-deazauridine",
  "field": "Oncology and biomedicine",
  "definition": "A synthetic analogue of nucleoside uridine lacking a ring nitrogen in the 3-position. 3-deazauridine inhibits cytidine synthase, thereby reducing intracellular levels of cytidine and deoxycytidine and disrupting DNA and RNA synthesis. This agent may trigger apoptosis and enhance differentiation of neoplastic cells.",
  "synonyms": [
    "deazauridine"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/3-deazauridine/"
}