dendritic cell-idiotype-keyhole limpet hemocyanin vaccine
Term · Oncology and biomedicine · MLC-T-ONC-012967
A cell-based vaccine composed of allogeneic dendritic cells (DC), pulsed with patient-specific non-Hodgkin's lymphoma idiotype (Id) determinants conjugated to keyhole limpet hemocyanin (KLH), with potential antitumor activity. Upon administration, this vaccine may stimulate the host immune system to mount a specific cytotoxic T-lymphocyte (CTL) response against Id-expressing lymphoma cells, resulting in tumor cell lysis.
| Identifier | MLC-T-ONC-012967 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | DC-Id-KLH vaccine |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-012967",
"term": "dendritic cell-idiotype-keyhole limpet hemocyanin vaccine",
"field": "Oncology and biomedicine",
"definition": "A cell-based vaccine composed of allogeneic dendritic cells (DC), pulsed with patient-specific non-Hodgkin's lymphoma idiotype (Id) determinants conjugated to keyhole limpet hemocyanin (KLH), with potential antitumor activity. Upon administration, this vaccine may stimulate the host immune system to mount a specific cytotoxic T-lymphocyte (CTL) response against Id-expressing lymphoma cells, resulting in tumor cell lysis.",
"abbreviation": "DC-Id-KLH vaccine",
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/dendritic-cell-idiotype-keyhole-limpet-hemocyanin-vaccine/"
}
Record 5,811 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.