MLchartDataset catalogue

dendritic cell-idiotype-keyhole limpet hemocyanin vaccine

Term · Oncology and biomedicine · MLC-T-ONC-012967

A cell-based vaccine composed of allogeneic dendritic cells (DC), pulsed with patient-specific non-Hodgkin's lymphoma idiotype (Id) determinants conjugated to keyhole limpet hemocyanin (KLH), with potential antitumor activity. Upon administration, this vaccine may stimulate the host immune system to mount a specific cytotoxic T-lymphocyte (CTL) response against Id-expressing lymphoma cells, resulting in tumor cell lysis.

Table 1. Record
IdentifierMLC-T-ONC-012967
FieldOncology and biomedicine
AbbreviationDC-Id-KLH vaccine
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-012967",
  "term": "dendritic cell-idiotype-keyhole limpet hemocyanin vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A cell-based vaccine composed of allogeneic dendritic cells (DC), pulsed with patient-specific non-Hodgkin's lymphoma idiotype (Id) determinants conjugated to keyhole limpet hemocyanin (KLH), with potential antitumor activity. Upon administration, this vaccine may stimulate the host immune system to mount a specific cytotoxic T-lymphocyte (CTL) response against Id-expressing lymphoma cells, resulting in tumor cell lysis.",
  "abbreviation": "DC-Id-KLH vaccine",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/dendritic-cell-idiotype-keyhole-limpet-hemocyanin-vaccine/"
}

Record 5,811 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.