Daniquidone

{
  "id": "MLC-T-ONC-012911",
  "term": "Daniquidone",
  "field": "Oncology and biomedicine",
  "definition": "A water-insoluble heterocyclic amide with potential antineoplastic activity. Daniquidone inhibits topoisomerases I and II, thereby inhibiting DNA replication and repair, and RNA and protein synthesis. The acetylated form of daniquidone is highly toxic and is capable of inducing unscheduled DNA synthesis; rapid acetylators are more likely to experience toxicity with this agent.",
  "synonyms": [
    "batracylin"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/daniquidone/"
}