Dapsone gel, 5%

{
  "id": "MLC-T-ONC-012920",
  "term": "Dapsone gel, 5%",
  "field": "Oncology and biomedicine",
  "definition": "A gel containing 5% (w/w) dapsone, a synthetic derivative of diamino-sulfone with anti-infective properties. A structural analog of p-aminobenzoic acid (PABA), dapsone inhibits dihydropteroate synthase (DHPS), an enzyme important in folate synthesis, resulting in a depletion of the folate pool and a reduction in the amount of thymidylate available for DNA synthesis.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/dapsone-gel-5-percent/"
}