Depth of coverage

{
  "id": "MLC-T-ONC-002369",
  "term": "Depth of coverage",
  "field": "Oncology and biomedicine",
  "definition": "Refers to the number of times a nucleotide is read during sequencing. A greater depth of coverage can increase confidence in the final results. Deep coverage aids in differentiating sequencing errors from single nucleotide polymorphisms. This can be specifically useful when a patient has a mosaicism or when a tumor is heterogeneous for a mutation.",
  "references": [
    "NCI Dictionary of Genetics Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/depth-of-coverage/"
}