ditiocarb sodium

{
  "id": "MLC-T-ONC-013082",
  "term": "ditiocarb sodium",
  "field": "Oncology and biomedicine",
  "definition": "The sodium salt form of ditiocarb, an active metabolite of disulfiram, with potential antineoplastic and chemosensitizing activities. Upon administration, ditiocarb sodium may form a complex with copper (Cu), a metal that selectively accumulates in cancer cells. This complex may inhibit the nuclear factor-kB (NF-kB) pathway activated by tumor hypoxia, thereby inhibiting tumor cell growth. It may also reverse chemoresistance and enhance cytotoxicity of other chemotherapeutic agents.",
  "synonyms": [
    "sodium diethyldithiocarbamate"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/ditiocarb-sodium/"
}