Esuberaprost sodium
Term · Oncology and biomedicine · MLC-T-ONC-013443
The sodium salt form of esuberaprost, the 314-d isomer of beraprost, with potential anti-inflammatory activity. Upon administration, esuberaprost activates the prostaglandin E2 receptor EP4 subtype (PTGER4; EP4), and inhibits the nuclear factor-kappa B (NF-kB) pro-inflammatory pathway. This may attenuate cytokine production and decrease inflammation.
| Identifier | MLC-T-ONC-013443 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | beraprost-314d |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-013443",
"term": "Esuberaprost sodium",
"field": "Oncology and biomedicine",
"definition": "The sodium salt form of esuberaprost, the 314-d isomer of beraprost, with potential anti-inflammatory activity. Upon administration, esuberaprost activates the prostaglandin E2 receptor EP4 subtype (PTGER4; EP4), and inhibits the nuclear factor-kappa B (NF-kB) pro-inflammatory pathway. This may attenuate cytokine production and decrease inflammation.",
"synonyms": [
"beraprost-314d"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/esuberaprost-sodium/"
}
Record 6,940 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.