sodium dichloroacetate

{
  "id": "MLC-T-ONC-016795",
  "term": "sodium dichloroacetate",
  "field": "Oncology and biomedicine",
  "definition": "The sodium salt of dichloroacetic acid with potential antineoplastic activity. Dichloroacetate ion inhibits pyruvate dehydrogenase kinase, resulting in the inhibition of glycolysis and a decrease in lactate production. This agent may stimulate apoptosis in cancer cells by restoring normal mitochondrial-induced apoptotic signaling.",
  "abbreviation": "DCA",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/sodium-dichloroacetate/"
}