MLchartDataset catalogue

DDB2 gene

Term · Oncology and biomedicine · MLC-T-ONC-002306

A gene that makes a protein involved in many cell functions, including the repair of damaged DNA. Mutations (changes) in the DDB2 gene may cause cells to lose their ability to repair damaged DNA, which may lead to abnormal cell growth. DDB2 gene mutations have been found in an inherited condition called xeroderma pigmentosum. People with this condition have a very high risk of developing skin cancer and other types of cancer.

Table 1. Record
IdentifierMLC-T-ONC-002306
FieldOncology and biomedicine
ReferencesNCI Dictionary of Cancer Terms
Record as JSON
{
  "id": "MLC-T-ONC-002306",
  "term": "DDB2 gene",
  "field": "Oncology and biomedicine",
  "definition": "A gene that makes a protein involved in many cell functions, including the repair of damaged DNA. Mutations (changes) in the DDB2 gene may cause cells to lose their ability to repair damaged DNA, which may lead to abnormal cell growth. DDB2 gene mutations have been found in an inherited condition called xeroderma pigmentosum. People with this condition have a very high risk of developing skin cancer and other types of cancer.",
  "references": [
    "NCI Dictionary of Cancer Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/ddb2-gene/"
}

Record 5,736 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.