disaccharide tripeptide glycerol dipalmitoyl
Term · Oncology and biomedicine · MLC-T-ONC-013078
A lipophilic disaccharide tripeptide derivative of muramyl dipeptide (MDP) with immunomodulatory activity. Disaccharide tripeptide glycerol dipalmitoyl (DTP-GDP)stimulates macrophage activity and increases serum levels of tumor necrosis factor alpha (TNF alpha), neopterin, interleukin (IL)-1 alpha, IL-1 beta, IL-6, IL-8, and IL-12, which may activate host immune system antitumor functions. DTP-GDP may be packaged in liposomes for improved delivery. The immunomodulatory effects of this agent may be superior to those of MDP.
| Identifier | MLC-T-ONC-013078 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | DTP-GDP |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-013078",
"term": "disaccharide tripeptide glycerol dipalmitoyl",
"field": "Oncology and biomedicine",
"definition": "A lipophilic disaccharide tripeptide derivative of muramyl dipeptide (MDP) with immunomodulatory activity. Disaccharide tripeptide glycerol dipalmitoyl (DTP-GDP)stimulates macrophage activity and increases serum levels of tumor necrosis factor alpha (TNF alpha), neopterin, interleukin (IL)-1 alpha, IL-1 beta, IL-6, IL-8, and IL-12, which may activate host immune system antitumor functions. DTP-GDP may be packaged in liposomes for improved delivery. The immunomodulatory effects of this agent may be superior to those of MDP.",
"abbreviation": "DTP-GDP",
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/disaccharide-tripeptide-glycerol-dipalmitoyl/"
}
Record 6,056 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.