MLchartDataset catalogue

disaccharide tripeptide glycerol dipalmitoyl

Term · Oncology and biomedicine · MLC-T-ONC-013078

A lipophilic disaccharide tripeptide derivative of muramyl dipeptide (MDP) with immunomodulatory activity. Disaccharide tripeptide glycerol dipalmitoyl (DTP-GDP)stimulates macrophage activity and increases serum levels of tumor necrosis factor alpha (TNF alpha), neopterin, interleukin (IL)-1 alpha, IL-1 beta, IL-6, IL-8, and IL-12, which may activate host immune system antitumor functions. DTP-GDP may be packaged in liposomes for improved delivery. The immunomodulatory effects of this agent may be superior to those of MDP.

Table 1. Record
IdentifierMLC-T-ONC-013078
FieldOncology and biomedicine
AbbreviationDTP-GDP
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-013078",
  "term": "disaccharide tripeptide glycerol dipalmitoyl",
  "field": "Oncology and biomedicine",
  "definition": "A lipophilic disaccharide tripeptide derivative of muramyl dipeptide (MDP) with immunomodulatory activity. Disaccharide tripeptide glycerol dipalmitoyl (DTP-GDP)stimulates macrophage activity and increases serum levels of tumor necrosis factor alpha (TNF alpha), neopterin, interleukin (IL)-1 alpha, IL-1 beta, IL-6, IL-8, and IL-12, which may activate host immune system antitumor functions. DTP-GDP may be packaged in liposomes for improved delivery. The immunomodulatory effects of this agent may be superior to those of MDP.",
  "abbreviation": "DTP-GDP",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/disaccharide-tripeptide-glycerol-dipalmitoyl/"
}

Record 6,056 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.