MLchartDataset catalogue

dicumarol

Term · Oncology and biomedicine · MLC-T-ONC-013042

A hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicumarol is a competitive inhibitor of vitamin K epoxide reductase; thus, it inhibits vitamin K recycling and causes depletion of active vitamin K in blood. This prevents the formation of the active form of prothrombin and several other coagulant enzymes, and inhibits blood clotting.

Table 1. Record
IdentifierMLC-T-ONC-013042
FieldOncology and biomedicine
Synonymsbishydroxycoumarin; dicoumarol
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-013042",
  "term": "dicumarol",
  "field": "Oncology and biomedicine",
  "definition": "A hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicumarol is a competitive inhibitor of vitamin K epoxide reductase; thus, it inhibits vitamin K recycling and causes depletion of active vitamin K in blood. This prevents the formation of the active form of prothrombin and several other coagulant enzymes, and inhibits blood clotting.",
  "synonyms": [
    "bishydroxycoumarin",
    "dicoumarol"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/dicumarol/"
}

Record 5,963 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.