dicumarol
Term · Oncology and biomedicine · MLC-T-ONC-013042
A hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicumarol is a competitive inhibitor of vitamin K epoxide reductase; thus, it inhibits vitamin K recycling and causes depletion of active vitamin K in blood. This prevents the formation of the active form of prothrombin and several other coagulant enzymes, and inhibits blood clotting.
| Identifier | MLC-T-ONC-013042 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | bishydroxycoumarin; dicoumarol |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-013042",
"term": "dicumarol",
"field": "Oncology and biomedicine",
"definition": "A hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicumarol is a competitive inhibitor of vitamin K epoxide reductase; thus, it inhibits vitamin K recycling and causes depletion of active vitamin K in blood. This prevents the formation of the active form of prothrombin and several other coagulant enzymes, and inhibits blood clotting.",
"synonyms": [
"bishydroxycoumarin",
"dicoumarol"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/dicumarol/"
}
Record 5,963 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.