MLchartDataset catalogue

Didemnin B

Term · Oncology and biomedicine · MLC-T-ONC-013043

A cyclic depsipeptide extracted from the Caribbean tunicate Trididemnum cyanophorum. Didemnin B activates caspase, thereby inducing apoptosis, and prevents eukaryotic elongation factor 2 (eEF-2)-dependent translocation, thereby inhibiting protein synthesis. This agent also has immunosuppressive and antiviral properties.

Table 1. Record
IdentifierMLC-T-ONC-013043
FieldOncology and biomedicine
Synonymsdidemnin
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON 
{
  "id": "MLC-T-ONC-013043",
  "term": "Didemnin B",
  "field": "Oncology and biomedicine",
  "definition": "A cyclic depsipeptide extracted from the Caribbean tunicate Trididemnum cyanophorum. Didemnin B activates caspase, thereby inducing apoptosis, and prevents eukaryotic elongation factor 2 (eEF-2)-dependent translocation, thereby inhibiting protein synthesis. This agent also has immunosuppressive and antiviral properties.",
  "synonyms": [
    "didemnin"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/didemnin-b/"
}

Record 5,964 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.