dideoxyadenosine

{
  "id": "MLC-T-ONC-013044",
  "term": "dideoxyadenosine",
  "field": "Oncology and biomedicine",
  "definition": "A synthetic nucleoside analogue of deoxyadenosine and a prodrug of didanosine in which the 3' hydroxyl group on the ribose moiety is replaced by a hydrogen atom. Dideoxyadenosine competitively inhibits adenylyl cyclase, thereby reducing levels of cyclic adenosine monophosphate (cAMP). By inhibiting cAMP-mediated gene activation in tumor cells, this agent may retard tumor cell proliferation.",
  "abbreviation": "ddA",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/dideoxyadenosine/"
}