desipramine hydrochloride

{
  "id": "MLC-T-ONC-012989",
  "term": "desipramine hydrochloride",
  "field": "Oncology and biomedicine",
  "definition": "The hydrochloride salt form of desipramine, a secondary amine tricyclic antidepressant (TCA). In the central nervous system (CNS), desipramine hydrochloride blocks the re-uptake of neurotransmitters, including norepinephrine and serotonin. This leads to an increase in the amount of these neurotransmitters in the synaptic cleft and prolongs their activities postsynaptically.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/desipramine-hydrochloride/"
}