DNP-modified autologous renal cell carcinoma tumor cell vaccine

{
  "id": "MLC-T-ONC-013112",
  "term": "DNP-modified autologous renal cell carcinoma tumor cell vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A cancer vaccine consisting of autologous renal cell carcinoma (RCC) tumor cells modified with the hapten 2,4-dinitrophenol (DNP) with potential immunostimulating and antineoplastic activities. Administration of DNP-modified autologous renal cell carcinoma tumor cell vaccine may induce a cytotoxic T-lymphocyte (CTL) response against renal cell carcinoma tumor cells. DNP conjugation may enhance the immunogenicity of weakly immunogenic antigens.",
  "synonyms": [
    "dinitrophenyl-modified autologous renal cell carcinoma tumor cell vaccine"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/dnp-modified-autologous-renal-cell-carcinoma-tumor-cell-vaccine/"
}