autologous dinitrophenyl-modified ovarian cancer vaccine

{
  "id": "MLC-T-ONC-011609",
  "term": "autologous dinitrophenyl-modified ovarian cancer vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A cancer vaccine consisting of autologous ovarian cancer cell peptide antigens conjugated to the hapten 2,4-dinitrophenol (DNP) with potential immunostimulating and antineoplastic activities. Administration of autologous dinitrophenyl-modified ovarian cancer vaccine may induce a cytotoxic T-lymphocyte (CTL) response against ovarian cancer cells. DNP conjugation may enhance the immunogenicity of weakly immunogenic antigens.",
  "synonyms": [
    "autologous DNP-modified ovarian cancer vaccine"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-dinitrophenyl-modified-ovarian-cancer-vaccine/"
}