ovarian tumor antigen-activated autologous dendritic cell vaccine

{
  "id": "MLC-T-ONC-015725",
  "term": "ovarian tumor antigen-activated autologous dendritic cell vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A dendritic cell (DC)-based cancer vaccine composed of autologous dendritic cells (DCs) activated with an ovarian tumor cell lysate containing tumor-associated antigens (TAAs) with potential immunostimulatory and antineoplastic activities. Upon administration, the ovarian tumor antigen-activated autologous DC vaccine may stimulate an anti-tumoral cytotoxic T-lymphocyte (CTL) response against ovarian cancer cells expressing ovarian tumor cell-specific antigens, which may result in ovarian tumor cell lysis.",
  "synonyms": [
    "DCVAC/OvCa"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/ovarian-tumor-antigen-activated-autologous-dendritic-cell-vaccine/"
}