autologous ovarian cancer-specific antigens-pulsed dendritic cells Cellgram-DC

{
  "id": "MLC-T-ONC-011731",
  "term": "autologous ovarian cancer-specific antigens-pulsed dendritic cells Cellgram-DC",
  "field": "Oncology and biomedicine",
  "definition": "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with ovarian cancer-specific antigen(s), with potential immunostimulatory and antineoplastic activities. Upon subcutaneous administration of the autologous ovarian cancer-specific antigens-pulsed DCs Cellgram-DC near the lymph nodes, the DCs stimulate a specific cytotoxic T-lymphocyte (CTL)-mediated immune response against the ovarian cancer cells expressing the antigens, resulting in tumor cell lysis.",
  "synonyms": [
    "Cellgram-DC",
    "autologous dendritic cells Cellgram-DC pulsed with ovarian cancer-specific antigens",
    "autologous ovarian cancer-specific antigens-pulsed DCs Cellgram-DC"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-ovarian-cancer-specific-antigens-pulsed-dendritic-cells-cellgram-dc/"
}