autologous ovarian cancer-specific cytotoxic T lymphocytes

{
  "id": "MLC-T-ONC-011732",
  "term": "autologous ovarian cancer-specific cytotoxic T lymphocytes",
  "field": "Oncology and biomedicine",
  "definition": "A preparation of autologous cytotoxic T lymphocytes (CTLs) genetically modified to target a not yet disclosed ovarian cancer-specific tumor-associated antigen (TAA), with potential immunomodulating and antineoplastic activities. After isolation, transduction, expansion in culture, and reintroduction into the patient, the autologous ovarian cancer-specific cytotoxic T lymphocytes (OC-CTLs) bind to and induce selective toxicity in tumor cells expressing the TAA.",
  "abbreviation": "OC-CTLs",
  "synonyms": [
    "autologous OC-CTLs",
    "autologous ovarian cancer-specific CTLs"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-ovarian-cancer-specific-cytotoxic-t-lymphocytes/"
}