MLchartDataset catalogue

autologous prostate cancer-specific antigens-pulsed dendritic cells Cellgram-DC-PC

Term · Oncology and biomedicine · MLC-T-ONC-011755

A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with prostate cancer (PC)-specific antigen(s), with potential immunostimulatory and antineoplastic activities. Upon administration of the autologous PC-specific antigens-pulsed DCs injected subcutaneously near the inguinal lymph nodes, the DCs stimulate a specific cytotoxic T-lymphocyte (CTL)-mediated immune response against the PC cells expressing the antigens, resulting in tumor cell lysis.

Table 1. Record
IdentifierMLC-T-ONC-011755
FieldOncology and biomedicine
SynonymsCellgram-DC-PC; autologous dendritic cells Cellgram-DC-PC pulsed with prostate cancer-specific antigens; autologous prostate cancer-specific antigens-pulsed DCs Cellgram-DC-PC
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-011755",
  "term": "autologous prostate cancer-specific antigens-pulsed dendritic cells Cellgram-DC-PC",
  "field": "Oncology and biomedicine",
  "definition": "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with prostate cancer (PC)-specific antigen(s), with potential immunostimulatory and antineoplastic activities. Upon administration of the autologous PC-specific antigens-pulsed DCs injected subcutaneously near the inguinal lymph nodes, the DCs stimulate a specific cytotoxic T-lymphocyte (CTL)-mediated immune response against the PC cells expressing the antigens, resulting in tumor cell lysis.",
  "synonyms": [
    "Cellgram-DC-PC",
    "autologous dendritic cells Cellgram-DC-PC pulsed with prostate cancer-specific antigens",
    "autologous prostate cancer-specific antigens-pulsed DCs Cellgram-DC-PC"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-prostate-cancer-specific-antigens-pulsed-dendritic-cells-cellgram-dc/"
}

Record 3,091 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.