autologous prostate cancer-specific antigens-pulsed dendritic cells Cellgram-DC-PC
Term · Oncology and biomedicine · MLC-T-ONC-011755
A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with prostate cancer (PC)-specific antigen(s), with potential immunostimulatory and antineoplastic activities. Upon administration of the autologous PC-specific antigens-pulsed DCs injected subcutaneously near the inguinal lymph nodes, the DCs stimulate a specific cytotoxic T-lymphocyte (CTL)-mediated immune response against the PC cells expressing the antigens, resulting in tumor cell lysis.
| Identifier | MLC-T-ONC-011755 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | Cellgram-DC-PC; autologous dendritic cells Cellgram-DC-PC pulsed with prostate cancer-specific antigens; autologous prostate cancer-specific antigens-pulsed DCs Cellgram-DC-PC |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-011755",
"term": "autologous prostate cancer-specific antigens-pulsed dendritic cells Cellgram-DC-PC",
"field": "Oncology and biomedicine",
"definition": "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with prostate cancer (PC)-specific antigen(s), with potential immunostimulatory and antineoplastic activities. Upon administration of the autologous PC-specific antigens-pulsed DCs injected subcutaneously near the inguinal lymph nodes, the DCs stimulate a specific cytotoxic T-lymphocyte (CTL)-mediated immune response against the PC cells expressing the antigens, resulting in tumor cell lysis.",
"synonyms": [
"Cellgram-DC-PC",
"autologous dendritic cells Cellgram-DC-PC pulsed with prostate cancer-specific antigens",
"autologous prostate cancer-specific antigens-pulsed DCs Cellgram-DC-PC"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/autologous-prostate-cancer-specific-antigens-pulsed-dendritic-cells-cellgram-dc/"
}
Record 3,091 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.