autologous MG-7-pulsed dendritic cell vaccine

{
  "id": "MLC-T-ONC-011699",
  "term": "autologous MG-7-pulsed dendritic cell vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A dendritic cell (DC)-based cancer vaccine composed of autologous DCs pulsed with the human gastric carcinoma-associated antigen MG7, with potential immunostimulatory and antineoplastic activities. Upon administration at the inguinal lymph nodes, autologous MG7-pulsed DC vaccine may stimulate the immune system to mount an anti-tumoral cytotoxic T-lymphocyte (CTL) response against MG7-expressing tumor cells, which may result in tumor cell lysis. MG7, a glycosylated protein sequence from the tumor-associated antigen (TAA) carcinoembryonic antigen (CEA), plays a key role in the development of certain tumor cell types.",
  "synonyms": [
    "autologous MG7-pulsed DC vaccine",
    "MG7-DC vaccine",
    "MG-7 antigen-pulsed autologous DC vaccine"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-mg-7-pulsed-dendritic-cell-vaccine/"
}