autologous monocyte-derived lysate-pulsed dendritic cells PV-001-DC

{
  "id": "MLC-T-ONC-011701",
  "term": "autologous monocyte-derived lysate-pulsed dendritic cells PV-001-DC",
  "field": "Oncology and biomedicine",
  "definition": "A cell-based cancer vaccine composed of autologous, monocyte-derived dendritic cells (mDCs) pulsed with tumor cell lysate containing tumor associated antigens (TAAs), with potential immunostimulatory and antineoplastic activities. Upon administration,the autologous tumor cell lysate-pulsed mDCs vaccine PV-001-DC may stimulate an anti-tumoral cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the patient's tumor cell-specific TAAs, which may result in tumor cell lysis.",
  "synonyms": [
    "autologous monocyte-derived lysate pulsed DCs PV-001-DC",
    "PV-001-dendritic cell"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-monocyte-derived-lysate-pulsed-dendritic-cells-pv-001-dc/"
}