Autologous renal cell carcinoma tumor lysate-pulsed dendritic cell vaccine

{
  "id": "MLC-T-ONC-011761",
  "term": "Autologous renal cell carcinoma tumor lysate-pulsed dendritic cell vaccine",
  "field": "Oncology and biomedicine",
  "term_source": "Autologous Renal Cell Carcinoma Tumor Lysate-Pulsed Dendritic Cell Vaccine",
  "definition": "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with renal cell carcinoma (RCC) tumor cell lysate containing tumor associated antigens (TAAs) with potential immunostimulatory and antineoplastic activities. Upon administration, autologous renal cell carcinoma tumor lysate-dendritic cell vaccine may stimulate anti-tumoral cytotoxic T-lymphocyte (CTL) and antibody responses against RCC tumor cells expressing RCC TAAs, resulting in RCC tumor cell lysis.",
  "abbreviation": "autologous RCC tumor lysate-DC vaccine",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-renal-cell-carcinoma-tumor-lysate-pulsed-dendritic-cell-vaccine/"
}