defibrotide sodium

{
  "id": "MLC-T-ONC-002333",
  "term": "defibrotide sodium",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A drug used to treat hepatic veno-occlusive disease (a condition in which small veins in the liver are blocked) in adults and children who also have kidney or lung problems after receiving a stem cell transplant. Defibrotide sodium may affect the cells that line the inside of blood vessels and may help improve blood flow inside the liver. Also called Defitelio.",
    "A polydeoxyribonucleotide with antithrombotic, thrombolytic, and fibrinolytic properties. Defibrotide sodium induces the release of prostaglandin 12 and reduces the expression of adhesion molecules on endothelial cells, thereby interfering with platelet and leukocyte adhesion to the endothelium."
  ],
  "synonyms": [
    "Defitelio"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/defibrotide-sodium/"
}