Dendritic cell-precision multiple antigen T lymphocytes
Term · Oncology and biomedicine · MLC-T-ONC-012969
A preparation of dendritic cell-precision multiple antigen T-cells (DC-PMAT) that have been induced to specifically target multiple undisclosed tumor-associated antigens (TAAs), with potential antitumor activity. Although the exact mechanism(s) of action through which DC-PMAT cells exert their effects has yet to be elucidated, upon infusion, these cells may stimulate the host immune system to mount a highly-specific cytotoxic T-lymphocyte (CTL) response against tumors expressing common TAAs, which leads to tumor cell lysis.
| Identifier | MLC-T-ONC-012969 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | DC-PMAT |
| Synonyms | dendritic cell-precision multiple antigen T cells |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-012969",
"term": "Dendritic cell-precision multiple antigen T lymphocytes",
"field": "Oncology and biomedicine",
"definition": "A preparation of dendritic cell-precision multiple antigen T-cells (DC-PMAT) that have been induced to specifically target multiple undisclosed tumor-associated antigens (TAAs), with potential antitumor activity. Although the exact mechanism(s) of action through which DC-PMAT cells exert their effects has yet to be elucidated, upon infusion, these cells may stimulate the host immune system to mount a highly-specific cytotoxic T-lymphocyte (CTL) response against tumors expressing common TAAs, which leads to tumor cell lysis.",
"abbreviation": "DC-PMAT",
"synonyms": [
"dendritic cell-precision multiple antigen T cells"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/dendritic-cell-precision-multiple-antigen-t-lymphocytes/"
}
Record 5,812 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.