dendritic cell-autologous lung tumor vaccine
Term · Oncology and biomedicine · MLC-T-ONC-012964
A cancer vaccine consisting of lymphocytes harvested from a patient with lung cancer and induced to become antigen-presenting cells (APCs) known as dendritic cells. The dendritic cells are transduced with the gene encoding an antigen specific to the patient's cancer and then returned to the patient. In the host, the altered cells stimulate the immune system to mount a primary T cell response against lung tumor cells expressing the target antigen. Dendritic cell-autologous lung tumor vaccines have been investigated for use in cancer immunotherapy.
| Identifier | MLC-T-ONC-012964 |
|---|---|
| Field | Oncology and biomedicine |
| Synonyms | DCVax-Lung |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-012964",
"term": "dendritic cell-autologous lung tumor vaccine",
"field": "Oncology and biomedicine",
"definition": "A cancer vaccine consisting of lymphocytes harvested from a patient with lung cancer and induced to become antigen-presenting cells (APCs) known as dendritic cells. The dendritic cells are transduced with the gene encoding an antigen specific to the patient's cancer and then returned to the patient. In the host, the altered cells stimulate the immune system to mount a primary T cell response against lung tumor cells expressing the target antigen. Dendritic cell-autologous lung tumor vaccines have been investigated for use in cancer immunotherapy.",
"synonyms": [
"DCVax-Lung"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/dendritic-cell-autologous-lung-tumor-vaccine/"
}
Record 5,808 of 17,721 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.