autologous dendritic cell/myeloma fusion vaccine

{
  "id": "MLC-T-ONC-011604",
  "term": "autologous dendritic cell/myeloma fusion vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A therapeutic cancer vaccine consisting of autologous dendritic cells (DCs) fused with patient-derived plasma cell (multiple) myeloma cells with potential immunostimulatory and antineoplastic activities. Upon administration, autologous DC/multiple myeloma fusions stimulate both helper and cytotoxic T-lymphocyte (CTL) responses through the presentation of internalized and newly synthesized tumor associated antigens (TAAs). This may promote cellular and humoral antitumor immune responses in patients with plasma cell myeloma.",
  "synonyms": [
    "autologous DC/multiple myeloma fusions",
    "DC/MM fusion vaccine",
    "DC/MM fusions",
    "DC/multiple myeloma fusions",
    "DC/plasma cell myeloma fusion"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-dendritic-cell-myeloma-fusion-vaccine/"
}