autologous dendritic cell-tumor fusion vaccine

{
  "id": "MLC-T-ONC-011607",
  "term": "autologous dendritic cell-tumor fusion vaccine",
  "field": "Oncology and biomedicine",
  "definition": "A therapeutic cancer vaccine consisting of autologous dendritic cells (DCs) fused with autologous tumor cells with potential immunostimulatory and antineoplastic activities. Autologous dendritic cell-tumor fusion vaccine is generated in vitro by mixing DCs and irradiated tumor cells harvested from individual patients and treating them with polyethylene glycol (PEG) to produce DC-tumor cell fusion hybrid cells. Upon administration, autologous dendritic cell-tumor fusion vaccine may elicit antitumor humoral and cellular immune responses.",
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/autologous-dendritic-cell-tumor-fusion-vaccine/"
}