Dibotermin alfa

{
  "id": "MLC-T-ONC-013039",
  "term": "Dibotermin alfa",
  "field": "Oncology and biomedicine",
  "definition": "A recombinant form of human bone morphogenetic protein 2 (rhBMP-2), with potential bone remodeling and osteoinductive activities. Following administration, dibotermin alfa induces signaling cascades, which leads to osteoblast differentiation, enhancement of bone repair and formation, and improvement of re-vascularization. This promotes bone healing. BMP-2, a protein belonging to the transforming growth factor beta (TGFb) superfamily of proteins, plays a key role in bone and cartilage formation.",
  "abbreviation": "rhBMP2",
  "synonyms": [
    "diotermin",
    "nebotermin"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/dibotermin-alfa/"
}