zinpentraxin alfa

{
  "id": "MLC-T-ONC-017673",
  "term": "zinpentraxin alfa",
  "field": "Oncology and biomedicine",
  "definition": "A fully recombinant form of the human pentraxin 2 (PTX2) protein with potential antifibrotic activity. Upon intravenous administration, zinpentraxin alfa may inhibit myofibroblast generation by preventing the differentiation of circulating monocytes into fibrocytes and profibrotic macrophages. PTX2 is a circulating plasma protein that belongs to the class of pattern recognition receptors (PRR) of the innate immune system.",
  "synonyms": [
    "pentraxin 2",
    "PRM-151/PTX2",
    "recombinant human PTX2",
    "recombinant human pentraxin 2",
    "recombinant human serum amyloid P"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/zinpentraxin-alfa/"
}