Dornase alfa

{
  "id": "MLC-T-ONC-013149",
  "term": "Dornase alfa",
  "field": "Oncology and biomedicine",
  "definition": "A recombinant human deoxyribonuclease I (rhDNAse) with selective DNA cleaving activity. Upon intrapleural administration, dornase alfa catalyzes the degradation of extracellular DNA in airway secretions, which can reduce their viscosity. Thus, dornase alfa may both promote the clearing of airway mucus and improve pulmonary function.",
  "synonyms": [
    "recombinant human deoxyribonuclease I",
    "recombinanthuman deoxyribonuclease I"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/dornase-alfa/"
}