recombinant interferon alfa-2b

{
  "id": "MLC-T-ONC-007259",
  "term": "recombinant interferon alfa-2b",
  "field": "Oncology and biomedicine",
  "definitions": [
    "A drug used alone or with other drugs to treat adults with AIDS-related Kaposi sarcoma, hairy cell leukemia, certain types of follicular lymphoma or melanoma, genital warts or perianal warts, or chronic hepatitis B or C. It is also being studied in the treatment of other types of cancer and other conditions. Recombinant interferon alfa-2b is a form of interferon alfa (a substance normally made by cells in the immune system) that is made in the laboratory. It is a type of cytokine and a type of immunomodulating agent. Also called IFN alpha-2B, interferon alfa-2b, and Intron A.",
    "A non-glycosylated recombinant interferon with antiviral and antineoplastic activities. Alfa interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose protein products mediate antiviral, antiproliferative, anticancer, and immune-modulating effects."
  ],
  "synonyms": [
    "IFN alpha-2B",
    "interferon alfa-2b",
    "Intron A",
    "interferon alfa-2B",
    "interferon alpha-2b",
    "interferon alfa 2b"
  ],
  "references": [
    "NCI Dictionary of Cancer Terms",
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/recombinant-interferon-alfa-2b/"
}