Liposomal interleukin-2
Term · Oncology and biomedicine · MLC-T-ONC-014823
A formulation in which liposomes are loaded with the cytokine interleukin-2 (IL-2). By activating cytotoxic T lymphocytes, such as lymphokine-activated killer cells, and increasing levels of the cytotoxic cytokines interferon-gamma (IFN-gamma) and transforming growth factor-beta (TGF-beta), IL-2 may exhibit antitumoral activity. Liposomal formulations of IL-2 may promote entry of the cytokine into target tumor cells and may be used as an immunoadjuvant in cancer vaccine therapy.
| Identifier | MLC-T-ONC-014823 |
|---|---|
| Field | Oncology and biomedicine |
| Abbreviation | IL-2 LIPO |
| Synonyms | interleukin-2 liposome; liposome encapsulated interleukin-2 |
| References | National Cancer Institute Thesaurus (CC BY 4.0) |
Record as JSON
{
"id": "MLC-T-ONC-014823",
"term": "Liposomal interleukin-2",
"field": "Oncology and biomedicine",
"definition": "A formulation in which liposomes are loaded with the cytokine interleukin-2 (IL-2). By activating cytotoxic T lymphocytes, such as lymphokine-activated killer cells, and increasing levels of the cytotoxic cytokines interferon-gamma (IFN-gamma) and transforming growth factor-beta (TGF-beta), IL-2 may exhibit antitumoral activity. Liposomal formulations of IL-2 may promote entry of the cytokine into target tumor cells and may be used as an immunoadjuvant in cancer vaccine therapy.",
"abbreviation": "IL-2 LIPO",
"synonyms": [
"interleukin-2 liposome",
"liposome encapsulated interleukin-2"
],
"references": [
"National Cancer Institute Thesaurus"
],
"url": "https://mlchart.com/terminology/oncology/liposomal-interleukin-2/"
}
Record 10,174 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.