MLchartDataset catalogue

interleukin-2 gene

Term · Oncology and biomedicine · MLC-T-ONC-014482

The DNA sequence that encodes the protein cytokine interleukin-2 (IL-2). When introduced as the complementary DNA (cDNA) form into tumor cells by, for example, a genetically engineered adenovirus vector, the transfected IL-2 cDNA expresses IL-2 which may activate antitumoral natural killer cells and elicit an antitumoral cytotoxic T-cell response, resulting in an inhibition of tumor progression.

Table 1. Record
IdentifierMLC-T-ONC-014482
FieldOncology and biomedicine
SynonymsIL-2 gene
ReferencesNational Cancer Institute Thesaurus (CC BY 4.0)
Record as JSON
{
  "id": "MLC-T-ONC-014482",
  "term": "interleukin-2 gene",
  "field": "Oncology and biomedicine",
  "definition": "The DNA sequence that encodes the protein cytokine interleukin-2 (IL-2). When introduced as the complementary DNA (cDNA) form into tumor cells by, for example, a genetically engineered adenovirus vector, the transfected IL-2 cDNA expresses IL-2 which may activate antitumoral natural killer cells and elicit an antitumoral cytotoxic T-cell response, resulting in an inhibition of tumor progression.",
  "synonyms": [
    "IL-2 gene"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/interleukin-2-gene/"
}

Record 9,344 of 17,717 in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.