PEG-interleukin-2

{
  "id": "MLC-T-ONC-015910",
  "term": "PEG-interleukin-2",
  "field": "Oncology and biomedicine",
  "definition": "A complex of polyethylene glycol conjugated with human recombinant cytokine interleukin-2 (IL-2) with antineoplastic activity. PEG-interleukin-2 induces natural killer (NK) cell activity and the production of interferon-gamma (IFN-gamma), and enhances T cell-mediated cytotoxicity. Pegylation of IL-2 protects the cytokine from degradation.",
  "abbreviation": "PEG-IL-2",
  "synonyms": [
    "polyethylene glycol-modified recombinant interleukin-2"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/peg-interleukin-2/"
}