modified interleukin-2 DF6215

{
  "id": "MLC-T-ONC-015225",
  "term": "modified interleukin-2 DF6215",
  "field": "Oncology and biomedicine",
  "definition": "A modified and recombinant form of the human endogenous cytokine interleukin-2 (IL-2), with potential immunostimulating and antineoplastic activities. Upon administration, modified IL-2 DF6215 targets and binds to IL-2 receptor (IL-2R) expressed on CD8+ T effector cells and activates IL-2R-mediated signaling. This enhances cytotoxic T lymphocytes (CTLs)-mediated cytotoxic immune responses against tumor cells.",
  "synonyms": [
    "modified IL-2 DF6215"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/modified-interleukin-2-df6215/"
}