pegylated IL-2 8MW2311

{
  "id": "MLC-T-ONC-015923",
  "term": "pegylated IL-2 8MW2311",
  "field": "Oncology and biomedicine",
  "definition": "A polyethylene glycol (PEG)-conjugated form of the cytokine interleukin-2 (IL-2), with potential immunopotentiating and antineoplastic activities. Upon administration, pegylated IL-2 8MW2311 activates the Janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling pathway. This induces the proliferation of CD8+ T cells, enhances tumor cell killing and decreases tumor cell proliferation. Pegylation of IL-2 protects the cytokine from degradation.",
  "synonyms": [
    "pegylated interleukin-2 8MW2311",
    "PEG-conjugated IL-2 8MW2311"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/pegylated-il-2-8mw2311/"
}