lebrikizumab

{
  "id": "MLC-T-ONC-014733",
  "term": "lebrikizumab",
  "field": "Oncology and biomedicine",
  "definition": "A humanized monoclonal antibody against interleukin 13 (IL-13) with immunosuppressive and anti-asthmatic activities. Lebrikizumab binds to IL-13 and inhibits IL-13-mediated pathways. IL-13, a cytokine mainly secreted by type 2 helper T cells, plays a key role in the induction of allergic inflammation.",
  "abbreviation": "TNX-650",
  "synonyms": [
    "monoclonal antibody TNX-650",
    "immunoglobulin G4, anti-(human interleukin 13) (human-mouse monoclonal MILR1444a gamma-4-chain), disulfide with human-mouse monoclonal MILR1444a kappa-chain, dimer",
    "anti-IL-13 humanized monoclonal antibody TNX-650"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/lebrikizumab/"
}