Lipegfilgrastim

{
  "id": "MLC-T-ONC-014797",
  "term": "Lipegfilgrastim",
  "field": "Oncology and biomedicine",
  "definition": "A long acting glyco-pegylated recombinant form of human granulocyte colony-stimulating factor (G-CSF), with hematopoietic activity. Similar to G-CSF, lipegfilgrastim binds to and activates specific cell surface receptors, and stimulates neutrophil progenitor proliferation and differentiation. Therefore, this agent may prevent the duration and incidence of chemotherapy-induced neutropenia. Compared to filgrastim, lipegfilgrastim has a prolonged plasma half-life.",
  "synonyms": [
    "pegylated granulocyte colony stimulating factor (human short isoform) O(sup 3.137)-((3,5-dideoxy-5-((N-((omega-methoxypoly(oxyethylene))carbonyl)glycyl)amino)-D- glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->6)-2-(acetylamino)-2-deoxy-alpha-D- galactopyranosyl)-des-(37-39)-(1-methionine)human granulocyte colony-stimulating factor (G-CSF, pluripoietin)"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/lipegfilgrastim/"
}