Lindera obtusiloba extract

{
  "id": "MLC-T-ONC-014788",
  "term": "Lindera obtusiloba extract",
  "field": "Oncology and biomedicine",
  "definition": "A dietary supplement composed of an ethanol extracted powder of Lindera obtusiloba, with potential antioxidant and anti-inflammatory activities. Upon administration, Lindera obtusiloba extract (LOE) may promote anti-oxidant activities through the activation of nuclear factor erythroid 2-related factor 2 (Nrf-2)/heme oxygenase 1 (HO-1)/ NAD(P)H dehydrogenase [quinone] 1 (NQO1), which reduces the production of reactive oxygen species (ROS) and lowers ROS-mediated oxidative stress. In addition, LOE may exert anti-inflammatory effects through the inhibition of the phosphorylation and activation of mitogen-activated protein kinases (MAPKs) and nuclear factor-kappa B (NF-kB).",
  "abbreviation": "LOE",
  "synonyms": [
    "L. obtusiloba extract"
  ],
  "references": [
    "National Cancer Institute Thesaurus"
  ],
  "url": "https://mlchart.com/terminology/oncology/lindera-obtusiloba-extract/"
}