LOD score

{
  "id": "MLC-T-ONC-004915",
  "term": "LOD score",
  "field": "Oncology and biomedicine",
  "definition": "A statistical estimate of whether two genetic loci are physically near enough to each other (or \"linked\") on a particular chromosome that they are likely to be inherited together. A LOD score of 3 or higher is generally understood to mean that two genes are located close to each other on the chromosome. In terms of significance, a LOD score of 3 means the odds are 1,000:1 that the two genes are linked and therefore inherited together. Also called logarithm of the odds score.",
  "synonyms": [
    "logarithm of the odds score"
  ],
  "references": [
    "NCI Dictionary of Genetics Terms"
  ],
  "url": "https://mlchart.com/terminology/oncology/lod-score/"
}